Dr Ritu Malik
e: Dr Ritu Malik

Ritu Malik, is presently associated with the Nanoporation project at IMSAT Dundee. She has worked with the formulation and characterization of drug delivery systems for targeted drug delivery with subsequent in vitro and in vivo evaluation of these systems. The research responsibilities as a research associate in the Pharmaceutics division of Central drug Research Institute (CDRI), India were formulation and characterization of Polylactide microparticles using Supercritical Fluid Technology [Solution Enhanced Dispersion of Supercritical Fluids] for pulmonary delivery and cocrystallization of antitubercular drugs with different coformers by Hot-stage melt- Polarised optical microscopy and solution crystallization method and received fellowship from the Royal Society of United Kingdom for the work. She was involved in the formulation and characterization of biodegradable nanoparticles for localization in the uterus and folic acid conjugated nanoparticles of methotrexate for targeting to colon cancer. She worked on extraction, isolation and identification of active constituents of Morinda Citrifolia using HPLC and TLC fingerprinting. She worked on transdermal formulations delivering pulsatile T and on the rational design of a drug delivery system for intervention in the episodic endocrine phenomenon in the Hypothalamo –Pituitary-Testicular (HPT) axis for in vivo performance and contraceptive efficacy during her Ph. D at CDRI with the Junior Research and Senior Research Fellowship from Council of Scientific and Industrial Research (CSIR), India. Concurrently she worked on implementation of mathematical model for the HPT axis and time varying model for in vitro in vivo correlation of transdermal systems. She is working as a postdoctoral research assistant in the nanobiolab, IMSAT on the preparation of the nanovesicular drug delivery systems for targeted delivery to cancer. She is working on the development of the formulations for MR imaging capabilities and ultrasound receptiveness. She is involved with the study of toxicity and drug release from nanocarriers with MRgFUS (nanoporation) and sonoporation in vitro using microscopy facilities.

Published manuscripts
  • R Malik, S Tondwal, K.S. Venkatesh, and A Misra Nano-scaffold matrices for size-controlled, pulsatile transdermal testosterone delivery: nanosize effects on the time dimension: Nanotechnology, 19(2008) 435101 doi 10.1088/0957-4484/19/43/435101.
  • R Malik, D Gupta, Amit Misra Localization of Biodegradable nanoparticles in the uterus following intravaginal instillation suggests a novel mode of contraception Nanotoxicology, Volume 2, Issue S1 2008, page S48.
Published manuscripts
  • Malik Ritu, Tondwal Shailesh, Venkatesh K Subramanian, Gupta Gopal, and Misra, Amit. Timing feedback-inhibition of the male reproductive hormone axis. Available from Nature Precedings (2008)
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